Searchable abstracts of presentations at key conferences in endocrinology

ea0026p350 | Steroid metabolism | ECE2011

Testosterone supplementation improves adipose tissue function in an animal model of metabolic syndrome

Morelli A , Maneschi E , Vignozzi L , Filippi S , Marchetta M , Mazzanti B , Calcagno A , Comeglio P , Cellai I , Vannelli G B , Maggi M

Introduction: Adipose tissue dysfunction is associated to metabolic syndrome (MetS), a clustering of cardio-metaboilic risk factors, including hypogonadism. We recently demonstrated that T supplementation was able to ameliorate the metabolic profile and reduce visceral fat accumulation in high-fat diet (HFD)-induced rabbit model of MetS.Methods: We evaluated the differentiation capacity of preadipocytes (rPAD) obtained from visceral fat of the following ...